Rachel J Roth Flach Selected Research

Phosphotransferases (Kinase)

1/2017	Map4k4 impairs energy metabolism in endothelial cells and promotes insulin resistance in obesity.
1/2016	Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function.
1/2016	Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.
12/2015	Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis.
11/2014	The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila.

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Rachel J Roth Flach Research Topics

Disease

5	Obesity 01/2017 - 12/2010
4	Inflammation (Inflammations) 11/2020 - 01/2013
4	Atherosclerosis 01/2019 - 12/2015
2	Hypoxia (Hypoxemia) 12/2016 - 06/2015
2	Non-alcoholic Fatty Liver Disease 06/2015 - 01/2014
1	Cardiomegaly (Heart Hypertrophy) 01/2022
1	Heart Failure 01/2022
1	Hypertension (High Blood Pressure) 11/2020
1	Fibrosis (Cirrhosis) 11/2020
1	Myocardial Infarction 01/2019
1	Hyperinsulinism (Hyperinsulinemia) 01/2016
1	Insulin Resistance 01/2016
1	Atherosclerotic Plaque (Atheroma) 12/2015
1	Foot Ulcer 09/2015
1	Warts (Wart) 11/2014
1	Type 2 Diabetes Mellitus (MODY) 01/2014
1	Infections 01/2013
1	Metabolic Diseases (Metabolic Disease) 12/2010

Drug/Important Bio-Agent (IBA)

5	Phosphotransferases (Kinase)IBA 01/2017 - 11/2014
4	MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA 01/2017 - 12/2015
3	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 06/2015
3	LipidsIBA 01/2017 - 06/2015
2	Mitogen-Activated Protein KinasesIBA 01/2016 - 12/2010
2	Protein Kinases (Protein Kinase)IBA 01/2016 - 12/2015
2	Triglycerides (Triacylglycerol)IBA 06/2015 - 01/2014
2	EnzymesIBA 01/2014 - 12/2010
1	Enalapril FDA LinkGeneric 01/2022
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2022
1	Therapeutic UsesIBA 11/2020
1	Angiotensin IIIBA 11/2020
1	2- (6- (5- chloro- 2- methoxyphenyl)- 4- oxo- 2- thioxo- 3,4- dihydropyrimidin- 1(2H)- yl)acetamideIBA 01/2019
1	Lipoproteins (Lipoprotein)IBA 01/2019
1	Peroxidase (Myeloperoxidase)IBA 01/2019
1	Insulin (Novolin)FDA Link 01/2016
1	Apolipoproteins E (ApoE)IBA 12/2015
1	fibroblast growth factor 21IBA 01/2015
1	Interleukin-6 (Interleukin 6)IBA 01/2015
1	Long-Acting Thyroid Stimulator (LATS)IBA 11/2014
1	CytokinesIBA 01/2014
1	Liposomes (Liposome)IBA 01/2014
1	Interleukin-1 (Interleukin 1)IBA 01/2014
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2014
1	Clodronic Acid (Clodronate)IBA 01/2014
1	P-SelectinIBA 01/2013
1	Cell Adhesion MoleculesIBA 01/2013
1	E-SelectinIBA 01/2013

Therapy/Procedure

2	Therapeutics 11/2020 - 12/2010
1	Surgical Amputation (Amputations) 09/2015